2. 29 Spa At this tranquil haven tucked inside the Masion on Peachtree, mind, body and spirit enrichments are inspired by the power of grape seed and its extract. "Wine down" with the Cream of the Crop facial that uses crushed grape seeds from vineyards of the famed Napa Valley Mondavi family to remove dead skin and reveal a glow. But don't stop there: the Savor the Wine body specialty replenishes thirsty skin with a rose and Cabernet cocoon treatment that leaves a silky finish (3376 Peachtree Rd. N.E., Atlanta; 404-995-7529).

3. Le Spa

A gem in the heart of L.A., the stylishly French Le Spa at Sofitel is a decadent experience in art and function. Attention to detail is key to its ambiance. If luxury is what you seek, the Ageless Beauty Facial is where the forces of energy and relaxation meet in harmony. Add on the patented Nanospa Immersion, exclusive to
Le Spa. The 30-minute megadose of oxygen-rich nanobubbles nourishes, revives and replenishes your skin from head to toe (8555 Beverly Blvd., Los Angeles; 310-228-6777).

4. Spa at The Stoneleigh

Everything is big in Texas, and The Spa at The Stoneleigh is no exception. This 5,200-square-foot luxury spa features six treatment rooms, a fitness center, hair salon and nail salon—all for your vanity's desire. Indulge in the Decadent Gold Youth! treatment, infused with actual 24-karat gold, which claims firmer, radiant skin from the first dose. Organic ingredients and holistic therapies, including the Shirodhara and Bindi treatments, allow you to take the spa up on its offer to "surrender, indulge and lose yourself" (2927 Maple Avenue, Dallas; 800-921-8498).